Pediatric Gram-Negative Bacteremia: Hidden Agenda
نویسندگان
چکیده
منابع مشابه
Gram-negative Bacteremia Produces Both Severe
A canine sepsis model that simulates the human cardiovascular response to septic shock was produced in 10 conscious unsedated dogs by implanting an Eschichia coli-infected clot into the peritoneum, resulting in bacteremia. By employing serial, simultaneous measurements of radionuclide scan-determined left ventricular (LV) ejection fraction (EF) and thermodilution cardiac index (CI), the end-dia...
متن کاملEmpiric combination therapy for gram-negative bacteremia.
BACKGROUND Empirical combination antibiotic regimens consisting of a β-lactam and an aminoglycoside are frequently employed in the pediatric population. Data to demonstrate the comparative benefit of empirical β-lactam combination therapy relative to monotherapy for culture-proven Gram-negative bacteremia are lacking in the pediatric population. METHODS We conducted a retrospective cohort stu...
متن کاملPolyclonal bacteremia due to gram-negative rods.
The frequency of, risk factors for, and outcome of polyclonal gram-negative bacteremia are still unknown. We investigated them in a prospective cohort study of patients for whom a blood culture yielded >/=1 species of gram-negative aerobic rod. For each patient, pulsed field gel electrophoresis (PFGE) was performed on 4 colonies of each morphologic type. Episodes of bacteremia were considered p...
متن کاملGram-negative bacteremia induces greater magnitude of inflammatory response than Gram-positive bacteremia
INTRODUCTION Bacteremia is recognized as a critical condition that influences the outcome of sepsis. Although large-scale surveillance studies of bacterial species causing bacteremia have been published, the pathophysiological differences in bacteremias with different causative bacterial species remain unclear. The objective of the present study is to investigate the differences in pathophysiol...
متن کاملLess is more: combination antibiotic therapy for the treatment of gram-negative bacteremia in pediatric patients.
IMPORTANCE Definitive combination antibiotic therapy with a β-lactam and an aminoglycoside for the treatment of gram-negative bacteremia is commonly prescribed in pediatric patients; however, its efficacy and toxicity relative to β-lactam monotherapy are unknown. OBJECTIVE To determine whether definitive combination antibiotic therapy affects mortality and nephrotoxicity in pediatric patients...
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ژورنال
عنوان ژورنال: Journal of Child Science
سال: 2018
ISSN: 2474-5871
DOI: 10.1055/s-0037-1618564